Uvavanyo lwe-COVID-19 Antigen kunye ne-Aehealth FIA Meter yenzelwe ukumiselwa kwe-vitro quantitative ye-SARS-CoV-2 kwi-swabs yeempumlo zabantu, i-swabs yomqala okanye amathe kubantu abarhanelwa ukuba bane-COVID-19 ngumboneleli wabo wezempilo.Inoveli coronaviruses yeyodidi lwe-β lweCoronavirus.I-COVID-19 sisifo esosulelayo esinamandla sokuphefumla.Ngokuqhelekileyo abantu basengozini.Okwangoku, izigulana ezosulelwe yinoveli coronavirus ngoyena mthombo wosulelo;abantu abosulelekileyo abangenazimpawu nabo banokuba ngumthombo wosulelo.Ngokusekelwe kuphando lwangoku lwe-epidemiological, ixesha lokufukamela yi-1 ukuya kwiintsuku ze-14, ubukhulu becala iintsuku ezi-3 ukuya kwezi-7.Iimpawu eziphambili ziquka umkhuhlane, ukukhathala kunye nokukhwehlela okomileyo.Ukuxinana kweempumlo, iimpumlo, umqala obuhlungu, i-myalgia kunye ne-diarrhea zifumaneka kwiimeko ezimbalwa.Iziphumo zovavanyo zezochongo lwe-SARS-CoV-2 nucleocapsid antigen.I-antigen ibonakala ngokubanzi kwiisampuli eziphezulu zokuphefumla okanye iisampulu ezisezantsi zokuphefumla ngexesha lesigaba esinzima sosulelo.Iziphumo ezilungileyo zibonisa ubukho be-antigens yentsholongwane, kodwa ukulungelelaniswa kweklinikhi kunye nembali yesigulane kunye nolunye ulwazi lokuxilonga luyimfuneko ukufumanisa imeko yokusuleleka.Iziphumo ezilungileyo azikuthinteli usulelo lwebhaktheriya okanye ukosuleleka kunye nezinye iintsholongwane.I-antigen efunyenweyo ayinakuba ngunobangela oqinisekileyo wesifo.Iziphumo ezibi azilukhupheli ngaphandle usulelo lwe-SARS-CoV-2 kwaye akufuneki lusetyenziswe njengesona siseko sonyango okanye izigqibo zolawulo lwezigulane, kubandakanya nezigqibo zolawulo losulelo.Iziphumo ezibi kufuneka ziqwalaselwe kumxholo wokuvezwa kwesigulane mva nje, imbali kunye nobukho beempawu zeklinikhi kunye neempawu ezihambelana ne-SARS-CoV-2 kwaye ziqinisekiswe ngovavanyo lwemolekyuli, ukuba kuyimfuneko, kulawulo lwesigulane.
Le khithi yokuvavanya ngokukhawuleza isekelwe kwiteknoloji ye-fluorescence immunoassay.Ngexesha lovavanyo, iincindi zesampulu zisetyenziswa kumakhadi ovavanyo.Ukuba kukho i-antigen ye-SARS-CoV-2 kwisicatshulwa, i-antigen iya kubophelela kwi-SARS-CoV-2 monoclonal antibody.Ngexesha lokuhamba kwe-lateral, i-complex iya kuhamba kunye ne-nitrocellulose membrane ukuya ekupheleni kwephepha elithathayo.Xa upasa umgca wovavanyo (umgca T, oqatywe nenye i-SARS-CoV-2 monoclonal antibody) ikhompleksi ibanjwa yi-SARS CoV-2 antibody kumgca wovavanyo.Ke ngoko okukhona i-antigen ye-SARS-CoV-2 ikwisampulu, kokukhona iicomplexes ezininzi ziqokelelwa kumcu wovavanyo.Ubukhulu bomqondiso we-fluorescence ye-antibody ye-detector ibonisa isixa se-antigen ye-SARS CoV-2 ethathiweyo kunye ne-Aehealth FIA Meter ibonisa ugxininiso lwe-antigen ye-SARS-CoV-2 kumzekelo.
1. Gcina imveliso kwi-2-30 ℃, ubomi beshelufu buziinyanga ezili-18.
2. Ikhasethi yovavanyo kufuneka isetyenziswe kanye emva kokuvula isingxobo.
3. Ii-reagents kunye nezixhobo mazibe kwiqondo lobushushu begumbi (15-30℃) xa zisetyenziselwa uvavanyo.
Uvavanyo olululo:
Ilungile kubukho be-antigen ye-SARS-CoV-2.Iziphumo ezilungileyo zibonisa ubukho be-antigens yentsholongwane, kodwa ukulungelelaniswa kweklinikhi kunye nembali yesigulane kunye nolunye ulwazi lokuxilonga luyimfuneko ukumisela imeko yokusuleleka.Iziphumo ezincomekayo azilukhuhli usulelo lwebhaktiriya okanye ukosuleleka kunye nezinye iintsholongwane.I-antigen efunyenweyo isenokungabi ngunobangela oqinisekileyo wesifo.
Uvavanyo olubi:
Iziphumo ezibi ziyazicingela.Iziphumo zovavanyo ezingalunganga aziluthinteli usulelo kwaye akufuneki zisetyenziswe njengesona siseko sonyango okanye ezinye izigqibo zolawulo lwesigulane, kubandakanywa izigqibo zolawulo losulelo, ngakumbi xa kukho iimpawu zekliniki kunye neempawu ezihambelana ne-COVID-19, okanye kwabo bebekhe bagula. ukudibana nentsholongwane.Kucetyiswa ukuba ezi ziphumo ziya kuqinisekiswa yindlela yokuvavanya i-molecular, ukuba kuyimfuneko, kuLawulo lokulawula isigulane.