Iimpawu zoMsebenzi
Umda wokufumanisa: 0.08ng/mL;
Uluhlu lomgca: 0.08～10.00 ng/mL;
I-coefficient yolungelelwaniso lomgca R ≥0.990;
Ukuchaneka: ngaphakathi kwe-batch CV ngu-≤15%;phakathi kweebhetshi iCV yi ≤20%;
Ukuchaneka: ukutenxa okunxulumeneyo kweziphumo zomlinganiselo akuyi kuba ngaphezu kwe-±15% xa i-calibrator yokuchaneka esemgangathweni ivavanywa.
1. Gcina i-detector buffer ku-2～30℃.Isithinteli sizinzile ukuya kwiinyanga ezili-18.
2. Gcina i-Aehealth Ferritin Rapid Quantitative test cassette kwi-2～30℃, ubomi beshelufu bufikelela kwiinyanga ezili-18.
3. Ikhasethi yovavanyo kufuneka isetyenziswe kwiyure enye emva kokuvula ipakethi.
Iprotheyini ye-S100 yafunyanwa kwingqondo yenkomo nguMoore BW ngo-1965. Ithiywe ngegama leprotheyini enokuthi inyibilike kwi-100% ye-ammonium sulfate.Iinqununu ezimbini ze-α kunye ne-β zidibanisa ukwenza i-S100αα, i-S100αβ, kunye ne-S100-ββ.Phakathi kwazo, i-S100-β (S100αβ kunye ne-S100-ββ) iprotheni ikwabizwa ngokuba yiprotheni ephakathi kwe-nerve, kwaye abanye abaphengululi bayichaza njenge "protein ye-C-reactive" yengqondo.Iprotheyini ebophelelayo ye-asidi ye-calcium enobunzima bemolekyuli obungama-21KD iveliswa ikakhulu zii-astrocytes., Ngokuqulunqwa kweebhondi ze-disulfide ngamathambo e-cysteine, ikhona kwinkqubo ye-nervous central kwinani elikhulu ngendlela yomsebenzi we-dimer.
Iprotheni ye-S100-β inoluhlu olubanzi lwemisebenzi ye-biological kwaye idlala indima ebalulekileyo ekwandeni kweeseli, ukuhlukana, ukubonakaliswa kofuzo, kunye ne-cell apoptosis.Ngaphantsi kweemeko ze-physiological, i-protein ye-S100-β ebuchosheni ibonakaliswe buthathaka ngomhla we-14 wesigaba se-embryonic, kwaye inyuka ngokuhambelana nokukhula kunye nokuphuhliswa kwenkqubo ye-nervous, kwaye izinzile xa ikhulile.Iprotheni ye-S100-β i-neurotrophic factor in the physiological state, echaphazela ukukhula, ukwanda kunye nokuhlukana kweeseli ze-glial, igcina i-calcium homeostasis, kwaye idlala indima ethile ekufundeni nasekukhumbuleni, kwaye ikhuthaza ukuphuhliswa kwengqondo;xa abantu benokuphazamiseka kwengqondo Izifo, ukwenzakala kwengqondo (i-cerebral infarction, ukulimala kwengqondo, ukulimala kwengqondo emva kokuhlinzwa kwentliziyo, njl.njl.) okanye ukwenzakala kwi-nervous, i-S100-β protein ivuza kwi-cytosol ukuya kwi-cerebrospinal fluid, kwaye ingena egazini ngeyonakalisiweyo. isithintelo segazi-ingqondo, ngaloo ndlela Oku kukhokelela ekwandeni koxinzelelo lweprotheyini ye-S100-β egazini.
Njengomakishi we-biochemical wokulimala kwengqondo, i-S100-βIprotheyini inexesha elithile lokutshintsha iphethini emva kokulimala kwengqondo, kwaye inxulumene ngokusondeleyo neqondo lokulimala kwengqondo kunye ne-prognosis, kwaye inozinzo oluhle.Ukufunyaniswa kwexabiso layo lokugxininiswa kunceda kwisigwebo seklinikhi semithambo-luvo.Ubungakanani bezilonda zezicubu, umphumo wonyango kunye nokuxilongwa komntu.