I-FT3 kunye ne-FT4 zizishunqulelo zesiNgesi ze-serum yasimahla ye-triiodothyronine kunye ne-serum esimahla i-thyroxine, ngokulandelelanayo.
I-FT3 kunye ne-FT4 zezona zalathisi ezinovakalelo zokuxilongwa kwe-hyperthyroidism.
Ngenxa yokuba umxholo wabo awuchatshazelwa yi-thyroid ebopha i-globulin, banexabiso elibalulekileyo lesicelo ekuxilongweni kwe-hyperthyroidism kunye ne-hypothyroidism, ukuvavanywa kobunzima besifo, kunye nokubeka iliso kwimiphumo yonyango.
Ukuzimisela kwe-serum okanye amanqanaba e-plasma ye-Triiodothyronine (T3) ibonwa njengomlinganiselo obalulekileyo ekuhloleni umsebenzi we-thyroid.Iimpembelelo zayo kwiithishu ezijoliswe kuzo ziphindwe kane ngamandla kunezo ze-T4.I-T3 yasimahla (FT3) yifom engadityaniswanga kunye ne-biologically esebenzayo, emele kuphela i-0.2‐0.4 % ye-T3 iyonke.
Ukuzimisela kwe-T3 yamahhala kunenzuzo yokuzimela ngokuzimeleyo kwiinguqu kwiimpawu kunye neempawu zokubopha iiprotheni ezibophezelayo;Ke ngoko i-T3 yasimahla sisixhobo esiluncedo kwi-diagnostic yesiqhelo yeklinikhi yovavanyo lwesimo se-thyroid.Imilinganiselo ye-T3 yamahhala ixhasa ukuxilongwa okwahlukileyo kweengxaki ze-thyroid, ziyafuneka ukuze zihlukanise iintlobo ezahlukeneyo ze-hyperthyroidism, kunye nokuchonga izigulane ezine-T3 thyrotoxicosis.
Ukuzimisela kwe-serum okanye amanqanaba e-plasma ye-Thyroxine (T4) ibonwa njengomlinganiselo obalulekileyo ekuhloleni umsebenzi we-thyroid.I-Thyroxine (T4) yenye yeehomoni ezimbini ezinkulu eziveliswa lidlala lengqula (enye ibizwa ngokuba yi-triiodothyronine, okanye i-T3), i-T4 kunye ne-T3 zilawulwa yinkqubo yempendulo ebuthathaka ebandakanya i-hypothalamus kunye nedlala lepituitary.
I-T4 yamahhala ilinganiswa kunye ne-TSH xa ukuphazamiseka komsebenzi we-thyroid kukrokrelwa.Ukuzimisela kwe-fT4 kukwafanelekile ukubeka iliso kwi-thyrosuppressive therapy.Ukuzimisela kwe-T4 yamahhala kunenzuzo yokuzimela ngokuzimeleyo kwiinguqu kwiimpawu kunye neepropati ezibophezelayo zeeprotheni ezibophezelayo;
Umxholo we-FT3 ubaluleke kakhulu ekuxilongweni okwahlukileyo ukuba ingaba umsebenzi we-thyroid uyinto eqhelekileyo, i-hyperthyroid okanye i-hypothyroid.Kubaluleke kakhulu ukuxilongwa kwe-hyperthyroidism kwaye isalathisi esithile sokuxilongwa kwe-T3 hyperthyroidism.
Ukuzimisela kwe-FT4 yinxalenye ebalulekileyo yokuxilongwa kwenkqubo yekliniki kwaye ingasetyenziselwa njengendlela yokubeka iliso kwi-thyroid suppression therapy.Xa kurhanelwa ukungasebenzi kakuhle kwedlala lengqula, i-FT4 ne-TSH zidla ngokulinganiswa kunye.
Ixesha lokuposa: Nov-12-2021